New ICER Report Takes Hard Look At Spravato

The Institute for Clinical and Economic Review (ICER) released a statement on June 19th questioning the efficacy and cost effectiveness of treating resistant depression with esketamine (Spravato). The “report-at-a-glance”, linked *here*, summarizes the *full report*. ICER believes a reduction in price of 25-52% would be needed to improve cost-effectiveness. Spravato’s current list price of $32,400 per year exceeds the standard cost effective ratio that ICER has put in place.

When compared to the price of ketamine via IV infusion, Spravato in the first year reached a total of $36,500 while ketamine came in at $3,600. For persons seeking life-saving treatment, this barrier to entry poses a significant hurdle without proof of superiority to existing therapies (i.e. IV ketamine, TMS, ECT). While medications like Spravato are the future of depression treatment due to shortened response times and ease of use, we at Sunbelt Wellness Institute would like to see cost addressed by Janssen Pharmaceuticals.

Lastly, the policy recommendations highlighted in this report point towards changes at the level of the manufacturer. A comparison between esketamine and current treatments such as off-label ketamine via IV, transcranial magnetic stimulation (TMS), and electroconvulsive therapy (ECT) would allow real-world, long-term assessment of effectiveness. This last point means the most to patients who may have had prior success or failures with these highlighted therapies.

Sunbelt Wellness Institute is guided by TRUE NORTH – our unswerving moral compass which points us towards delivering effective therapies for our clientele. While we applaud the efforts of Janssen Pharmaceuticals in the development of a novel approach to combating treatment resistant depression, we share similar concerns with ICER over cost. We will continue to offer this service to those interested, but will make sure to be transparent and up-front about the fee structure. Sunbelt would like to make it clear that we are here for YOU! Ketamine Infusion Therapy is a proven treatment alternative backed by years of evidence-based research. If you or a loved one has suffered with treatment resistant depression, bipolar depression, PTSD, or chronic pain, contact us today to schedule a free 30 min consultation @ 904.830.6585 and visit to learn more.

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